Early Responses of Neural Cells (U87) to Particulate Matter Exposure: Cell Viability and Cytokine Concentration

نویسندگان

چکیده

Particulate Matter (PM) has a significant impact on human health and increases the risk of respiratory diseases. PM exposure is linked to various illnesses, including cardiovascular diseases, cancer, neurological pregnancy complications, contributes both mortality morbidity globally. can also influence autonomic nervous system. The evidence suggests that likelihood developing lung cancer continually rises with rise in concentration coarse PM10 (medium aerodynamic diameter less than or equal 10 μm). However, studies examining relationship between brain gliomas are scarce. In this study, U87 cells were exposed at three different concentrations effects evaluated by analyzing Lactate Dehydrogenase (LDH) activity, Interleukin-6 (IL-6) expression, cell viability using water-soluble tetrazolium assay. IL-6 varied time. did not LDH activity tested concentrations. These results provide crucial information for future research aimed understanding disease pathology.

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ژورنال

عنوان ژورنال: American Journal of Biochemistry and Biotechnology

سال: 2023

ISSN: ['1553-3468', '1558-6332']

DOI: https://doi.org/10.3844/ajbbsp.2023.65.70